Not yet known exactly what causes liver cancer cases. But in
some cases, cause liver cancer can occur because of certain chronic viral
hepatitis. Liver cancer occurs due to liver cells undergoing changes
(mutations) in the DNA, these DNA changes providing instruction material every
chemical process in the body. One result is cells can begin to grow out of
control and form tumors cancer cells ((mayoclinic.org, Liver Cancer, accessed
12 November 2014)).
Primary liver cancer begins in the growth of liver cancer
cells. In contrast with secondary liver cancer that originated elsewhere in the
body that has spread to the liver. Although the causes of cancer is not known,
but researchers are investigating various factors that allow an increase in the
occurrence of cancer in the future. Here are some of them
((cancerresearchuk.org, Risks and causes of liver cancer, accessed 12 November
2014)) ((medicalnewstoday.com, What is liver cancer? What causes liver cancer
?, accessed 12 November 2014)):
1. Hepatitis Virus Infection
Infection with hepatitis B or C in the long term, may
increase the risk of developing primary liver cancer because it causes damage
to the liver (cirrhosis). A person with hepatitis B or C infection, is expected
to not drink alcohol. Alcohol can increase the risk of cirrhosis or liver
cancer.
2. Experiencing Cirrhosis
Cirrhosis is scarring of the liver that result because of
tissue damage in advance. This scar tissue can cause problems with liver
function should be. Cirrhosis may increase the risk of liver cancer
(hepatocellular carcinoma or HCC). Risk varies, depending on the cause of
cirrhosis. Cirrhosis can be caused by:
Viral infections due to hepatitis B or C
Alcohol consumption in the long term
An inherited disease due to iron overload disorder
(hemochromatosis) and alpha 1 antitrypsin
3. Family History
A study conducted in the United States, found that people
who had a family (parent, brother or sister) who had been diagnosed with liver
cancer have double the risk of developing it. Another study jugamenunjukkan
cause an increased risk of liver cancer, which occurs in people with a father
and brother who were diagnosed with prostate cancer.
4. Immune Low
People who have weakened immune systems, such as people with
HIV / AIDS who are at risk of liver cancer is five times greater than healthy
people. HIV and AIDS immunity is lower. Then those who have undergone organ
transplants, people should take medication to stop rejection of the transplant.
Drugs give affects the immune system and increase the risk of liver cancer
doubled.
5. Appointment of gallbladder
People who have undergone removal of the gallbladder
(cholecystectomy) to remove gallstones, allowing an increased risk of liver
cancer. The increased risk may be due to increased pressure in the bile ducts
that cause long-term inflammation in the liver tissue.
6. Consumption of Alcohol
Excessive alcohol drinking more than five drinks a day, is
likely to increase the risk of liver cancer. Alcohol consumption above the
recommended dose of the current government which in the long term will lead to
cirrhosis, and also directly damage the DNA in the cells of the liver.
7. Smoking Habit
The habit of smoking can increase the risk of liver cancer.
Smokers who have had infections with hepatitis C virus or hepatitis B, can
increase the risk of cancer is higher. The smokers who drank alcohol in large
amounts, enabling higher cancer risk up to 10 times compared to people who do
not smoke or drink alcohol.
8. Excess Weight
The European Prospective Investigation into Cancer and
Nutrition (EPIC) study looked into the relationship between diet and cancer.
The researchers suggested that the risk of liver cancer is higher in people who
have a lot of weight in their waist (apple-shaped body). Obesity can also
increase the risk of other cancers such as colon cancer cause.
9. Diabetes
Someone who is having problems with diabetes, have a higher
risk of liver cancer compared with people without diabetes. This higher risk
may be due to higher insulin levels in diabetics and result in liver damage.
Some treatments for people with diabetes such as metformin can reduce the risk
of liver cancer.
10. Exposure to Chemicals
There is evidence to suggest that chemical substances vinyl
chloride, can increase the risk of liver cancer. Some limited evidence also
states that exposure to polychlorinated biphenyls and trichlorethylene can do.
Contact with these chemicals through jobs or the environment can cause liver
cancer.
11. Radiation X-ray or CT scan
Radiation from X-rays or scans can increase the risk of
liver cancer, but the risk is still very small. It is important to remember
that the X-rays and scans, is very important in diagnosing the disease so that
people can make the right treatment
12. The well water with arsenic
People who rely on well water containing arsenic, in the end
have a higher risk and significantly develop some conditions or diseases,
including liver cancer.
13. Aflatoxin
These substances can be found in moldy grain, peanuts, corn,
beans, soybeans and peanuts. The risk of liver cancer can occur because of the
possibility of consumption of these substances in the long term. This is a
problem that occurs in some poor countries than in industrialized countries.
14. Steroids Ababolic
The substances used by athletes, for example, the weight
lifters. This is actually a male hormone, use regularly and for a long time can
increase the risk of developing liver cancer, as well as several other types of
cancer
15. Gender
Presentation of the risk of liver cancer, which is higher in
men than women. However, some experts believe this not because of gender as
causes of breast cancer in women, but because of the characteristics and
lifestyle that the average man is doing. Such as the tendency of alcohol abuse
and smoking are higher than women.
Lifestyle factors such as alcohol consumption, smoking can
actually be pressed to reduce the possibility of liver cancer. However, a
number of other causes such as a history of liver cancer kaluarga, cirrhosis
and hepatitis virus infection can be immediately consulted on medical personnel
to do the prevention of liver cancer.
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