Liver Cancer Most Threatening Diseases Third World !

Liver Cancer - Did you know the cause of death Robbin Gibb main singer vocal group the Bee Gees? He died of liver cancer in the suffering for many years during his lifetime. And now proven liver cancer is the third most deadly diseases in the world. Globocan Based on data released by the International Agency for Research on Cancer (IARC), in 2008 was 748 000 cases of liver cancer were diagnosed. This disease is a cancer with the highest mortality rate in third, with 696,000 patients die each year.

Third World

More than 85% of these cases occur in developing countries, including Indonesia. Men are more susceptible to liver cancer than women. Of the 632,000 cases of liver cancer are diagnosed in the world, the ratio of male patients three times even, in extreme conditions, up to 6 times higher than female patients. "The difference in hormonal and behavioral men unleashed liver cancer," said Professor of the Faculty of Medicine Ali Sulaiman. In addition, Ali added, the habit of frequent nights out had a major impact on the entry of hepatitis A or B. "Plus endurance weaker men than women," he said. Liver cancer, or so-called killer who acted secretly though this cancer is one of the most lethal cancers according to data from the US National Cancer Institute. This disease usually does not show specific symptoms, and if there are more than 40% of patients do not experience symptoms of undiagnosed.

In this opportunity, I and this website will attempt to share and explain about liver cancer. May be useful for all of us and be equipped to prevent and treat liver cancer. Please scrutiny.

Liver cancer, or so-called killer who acted secretly though this cancer is one of the most lethal cancers according to data from the US National Cancer Institute. This disease usually does not show specific symptoms, and if there are more than 40% of patients do not experience symptoms of undiagnosed. Some of the symptoms of liver cancer among other things, weight loss, loss of appetite continuously, pain around the right shoulder, jaundice, and unusual fatigue. In Asian and African countries, most of these symptoms triggered by chronic infection with hepatitis B, whereas in Europe and Japan by hepatitis C. Other risk factors such as obesity, diabetes, smoking and alcohol consumption, as well as alfatoksin (toxin in peanuts). Treatment of liver cancer itself based on the type and stage of cancer as well as liver function of patients. If the stage of the cancer patient is still under 4 centimeters, some measures such as surgical removal of the tumor, liver transplants, and treatment uses high-frequency electricity (Radiofrecuency Ablation / RFA) can be done. When the stage of the cancer beyond 4 cm or advanced, palliative treatment (therapeutic target), better known as sorafenib so the solution.

Most liver cancer patients would not undergo heart surgery incision. They would have a transplant, the removal of the liver and cancer are exposed then transplanted liver from a donor. For patients with liver cancer, liver incision surgery feared would only bring back cancer elsewhere in the liver in a few years later. Moreover, according to some experts, if someone has had cancer of the liver, the heart of it are likely to suffer other tumors at the same time or in the future

On the other hand, the results of medical treatments, such as chemotherapy, kemoembolisasi, ablation, and proton beam therapy, too often disappointing. Moreover, there is rarely a comparison of each type of treatment. No wonder if liver cancer patients only exposed to a variety of treatment options without ever being able to obtain satisfaction over the result.

Here is a method of treatment of liver cancer that can be selected by the patient:

1. Systematic Chemotherapy

The most common systemic chemotherapy used is doxorubicin (Adriamycin) and 5-fluorouracil (5FU). These drugs are used simultaneously or in combination. Unfortunately, these drugs are very toxic, while the results are often disappointing.

In addition, there are also a drug called tamoxifen (Nolvadex). However, so far not shown significant benefits

Other drugs are octreotide (Sandostatin) is given as an injection to slow the progression of liver cancer tumors were great. But again, its efficacy has not been proven.

2. Hepatic Artery Infusion Chemotherapy

Normal liver gets 70 percent of its blood supply from the portal vein and 30 percent of the hepatic artery. Cancer of the liver gets blood supply exclusively from the hepatic artery. Therefore, emerging methods of chemotherapy through the hepatic artery directly to the tumor. In theory, drugs can be delivered to tumors without making people with drug intoxication.

However, in reality chemotherapy drugs can flow throughout the body. Consequently, intra-arterial chemotherapy can actually cause systemic side effects. This treatment method can also cause side effects regionally, such as gall bladder inflammation, ulcers in the intestines and stomach, and inflammation of the pancreas. In fact, patients with liver cancer in advanced stages could suffer liver failure after this treatment.

A radiologist usually performs the procedure through the hepatic artery. He will work closely with oncologists who determine the amount of chemotherapy received by patients at each treatment session. Some patients may undergo sessions are repeated at intervals of 6-12 weeks.

This procedure is done with the help of X-ray imaging of a catheter inserted into the femoral artery in the groin and threaded into the aorta (the main artery of the body). From the aorta, the catheter is pushed into the hepatic artery. After the branches of the hepatic artery feeding the liver cancer is identified, then the chemotherapy drug was infused. The whole procedure takes 1-2jam, then the catheter is removed.

Generally, liver tests improved or worsened during the procedure 2-3hari after chemotherapy via hepatic artery do. Increased liver tests are actually caused by the death of tumor cells and some tumor cells instead.

After chemotherapy through the hepatic artery is done, the patient may also experience abdominal pain and mild fever. This indicates that a more serious complications have developed.

3. Proton Beam Therapy

Proton Beam Therapy is a therapeutic technique that is able to deliver high doses of radiation in a defined local area. This therapy is also used in the treatment of other malignant tumors. Unfortunately, there is no evidence about the efficacy of this treatment method for liver cancer

4. Operations

Surgery performed on patients who had tumors less than five centimeters and is limited to the liver. Another requirement for surgery is no invasion of blood vessels to the heart.

5. penyayatan Heart

Slicing liver (liver resection) aimed to remove all of the tumor and surrounding liver tissue without leaving any tumor behind. This action can only be performed on patients who have small tumors three centimeters or less size, liver function perfectly, and without cirrhosis. However, because of the requirements that also then not many liver cancer patients to undergo a liver incision.

The biggest concern of slicing is that after surgery, the patient can experience liver failure. Liver failure can also occur if the remaining part of the heart was not adequate to provide the necessary support for life.

6. Liver Transplantation

Liver transplant could be one method of treatment for patients with end-stage liver cancer of various types, such as chronic hepatitis B and C or alcoholic cirrhosis. Figures survival for patients without liver cancer is 90 percent in one year, 80 percent in three years, and 75 percent within five years.

Liver transplantation is the best option for patients who have tumors with a size of less than five centimeters which also has signs of liver failure. In fact, liver transplantation in patients who had tumors measuring less than three centimeters, but has no involvement with the blood vessels can run well.

After transplant these patients are at risk of recurrence of liver cancer is less than 10 percent. On the other hand, patients who have tumors larger than five centimeters or with the involvement of the blood vessels at very high risk for experiencing recurrence of liver cancer.

In summary, slicing liver can be done for patients who have small tumors and normal liver function or no evidence of cirrhosis. Meanwhile, patients kaker mepunyai liver tumors or large yangbanyak could also undergo a liver transplant, but must be mitigated or alleviated by intra-arterial chemotherapy. The condition of patients did not have signs of severe liver failure.

7. Liver biopsy or suction

Liver cancer tissues can be sampled using a very thin needle. This technique is called fine needle aspiration. Meanwhile, when a larger needle is used to obtain a core network, then the technique is called a biopsy.

Radiologists commonly use CT scans to guide placement of the needle or perform a biopsy and fine needle aspiration. The most common risk of biopsy is bleeding, especially for liver cancer is a tumor that contains blood vessels.

Suctioning procedure is safer than a biopsy because they have a smaller risk of bleeding. Still, fine needle aspiration requires a pathologist with high skills.

If a patient has a risk factor for cancer of the liver, such as cirrhosis, chronic hepatitis B or C chronic hepatisis, and blood levels of AFP were up significantly, then the doctor usually conclude without performing a biopsy that the person has liver cancer.

Symptoms of Liver Cancer

Approximately three-quarters of cases of liver cancer are found in countries in Asia, such as China, Hong Kong, Taiwan, Korea and Japan. Liver cancer is also a disease that is very common in Sub-Saharan Africa, such as Mozambique and South Africa.

More than 20 cases of liver cancer per 100,000 population occurred in Southeast Asia and Sub-Saharan Africa. While in North America and Western Europe occurred less than five per 100,000 population.

The frequency of liver cancer in Alaska is comparable to that can be found in Southeast Asia. Meanwhile, the frequency of liver cancer in the United States in general have increased, especially cancer of chronic hepatitis C, a liver infection that causes liver cancer.

In 1990, the World Health Organization (WHO) estimates that there are approximately 430,000 new cases of liver cancer worldwide. The same amount also came from patients who died from the disease.

Early symptoms of liver cancer actually is varied. In countries that experienced the prevalence of this disease, liver cancer generally found in a very advanced stage. This happens for various reasons, including because of limited access to health services such as developing countries.

Countries in which the frequency of liver cancer is high, there are patients who are at risk of suffering from this disease. However, they suffer from liver cancer more aggressive. That is, they have tumors that reached an advanced stage that the symptoms of liver cancer is coming faster.

In contrast, patients in the areas that the frequency of liver cancer are much more likely to have liver cancer tumors that progress more slowly. In other words, they do not have symptoms that last longer.

Symptoms of liver cancer is the most common and usually signifies a very large tumor or liver involvement was very widespread is pain or cramping. In addition, weight loss and fever that can not be explained are the warning signs of liver cancer.

The apparition of liver cancer the most common early in a patient who does not have the complications of liver disease is the appearance of sudden complications. For example, the appearance of liquid suddenly.